Secretagogue One by MHP

Secretagogue one sachets Secretagogue-One is a proprietary blend of amino acids and precursor nutrients that has been formulated to enhance the body’s natural production of Human Growth Hormone (HGH).

It is produced in the USA by Maximum Human Performance (MHP) and is supplied in boxes that contain 30 (one dose) sachets.

MHP was founded by the former top-level bodybuilder Gerard Dente, and the company’s products are the favored supplements of a number of accomplished athletes—including, IFBB professional bodybuilder Craig Richardson—so the brand has a lot of credibility.

A viable option to Secretagogue One would be Prime Male. Arguably the best in it’s genre Prime Male gives it’s users an unrivalled testosterone and a many testimonials (even one from Rocky’s sparring partner Dolph Lundgren.

Prime Male is a seriously good formulation that is backed up by a 90 day day money back guarantee.

Click here to read our review of Prime Male

What is Secretagogue-One and how does it Work?

Secretagogue-One should not be confused with some of the dodgy HGH options that are sometimes used in the gym—or more probably injected in the locker room. The formulation contains no hormones of any kind. It is designed to stimulate the pituitary gland and encourage the body to increase natural hormone secretion.

Promised Secretagogue-Onebenefits include:

  • Helps decreases body fat
  • Improves lean body mass
  • Boosts energy
  • Supports immune functions
  • Improves bone density, memory, sex drive and skin texture

Key Ingredients

Each (13.2g) sachet provides a few supportive minerals, but the main ingredients are four proprietary blends: Anterior Pituitary Substance (25mg), Glycoamino Acid-Glucose Complex (4200mg), Novel Polyose Complex (1700mg), and Amino Acid Blend (5,000mg).

The amino acid blend appears to contain all the HGH releasers:

  • Glycine
  • L-Tyrosine
  • Glutamine
  • GABA
  • Pyroglutamic Acid
  • Arginine
  • Lysine

Without individual inclusion rates to go by it is hard to say how good the mix is likely to be, but the ingredients all have merit.

GABA stands out as being one of the most promising inclusions. Its HGH increasing abilities have been proven in several tests. In one study (Okayama University School of Medicine in Okayama, Japan) six men were given 2.5g of GABA and their HGH levels were tested at 15 minute intervals. A significant increase in HGH was noted at 30, 45, 60 and 90 minutes.

The HGH increasing abilities of Glutamine can be backed up by a study published in the American Journal of Clinical Nutrition, which indicated small amounts of the amino acid can significantly increase HGH levels.

Arginine and Lysine have an overrated reputation for increasing HGH when used alone, but appear to work very well in any blend that combines their powers.

Dosage – Secretagogue-One could be considered a healthy nightcap. One sachet should be mixed with 4 to 6oz. of water and then be consumed on an empty stomach just before going to bed. A four week break is required after three months of supplementation.

Secretagogue-One Customer Feedback

Customer feedback is mixed, but predominantly good.

“Very good taste. Easy to mix. Has given me more energy during workouts and seems to help with muscle soreness. I will be purchasing more of this when my supply runs out.”

“I have been using this product for years. It promotes a great sleep while releasing what our body needs.”

“The only negative aspect for me is I wake up during early morning hours sometimes when I take it.”

“I love this product. It makes my skin look so much better (younger) and I feel better while taking it.”

Secretagogue-One Health Considerations

MHP do not mention any side effects, and none of the ingredients are likely to be problematic, so negative issues are unlikely. Pregnant and nursing mothers should always play it safe though, and never take any form of supplement unless its use had been approved by their doctor. The same advice is offered to anyone who has an existing medical condition, any health worries or concerns, or who is taking medications.

Secretagogue-One Product Availability and Pricing

Secretagogue-One is stocked in many online stores and is also available from the MHP website, so most people should be able to source a supplier easily enough. It comes in a choice of two flavors (orange, lemon Ice) and costs around $30 to $45, depending on the supplier, but expect to pay double if you purchase Secretagogue-One directly from the MHP website.


There does not appear to be a money back guarantee.

The Bottom Line

Most Secretagogue-One suppliers offer reasonable pricing, so the cost of the product is not an issue unless buying directly from MHN, in which case it is probably a little too pricey for a product that does not come with a money back guarantee.

The use of proprietary blends makes it hard to gain a solid insight into the blend’s true potential just by looking at the ingredients used; so the fact that a good amount of customer feedback is available helps a lot and most Secretagogue-One users appear to be more than happy with the results obtained.

Is Secretagogue-One a HGH booster that really works? Very probably, but many other products are similarly good. Secretagogue-One may, however, prove a particularly good option for anyone who finds it hard to swallow capsules and/or hates fiddling about with measuring scoops.

Click here to view our list recommended testosterone boosters